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Showing posts with the label Viral Oncology

Drug-Resistance in Farm Animals Threatens Human Health

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Antimicrobial Drug : Drug-Resistance in Farm Animals Threatens Human Health https://antimicrobial.vaccineconferences.com/speaker-guidelines.php In high-economic countries, where antimicrobial  have been used on farms since the 1950s, should support the transition to sustainable animal production in low & middle income countries for e.g. through a global fund to subsidize improvements in farm-level bio-safety  and bio-security , the authors advocate in the study. The Netherlands and Denmark have made a tremendous effort to reduce antimicrobial use. But these required investments in clean infrastructure and training of farmers to follow good farming practices and practicing good hygiene on the farm can reduce drug resistance in farm animals. A survey report has been done from 2000 and 2018 focusing specifically on common food-borne  pathogens, including  Escherichia coli, Campylobacter spp., non-typhoidal Salmonella,  and  Staphylococcus...

The Bacterial Protein promoting Cancer

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Viral Oncology :  The Bacterial Protein promoting Cancer DNA K, a protein of the bacterium mycoplasma, interferes with the mycoplasma-infected cell's ability to respond to and repair DNA damage, a known origin of cancer.  Little or no mycoplasma DnaK DNA sequences were found associated with the tumor, which was fully developed, suggesting a hit-and-run or hide mechanism of transformation, indicating that the damage is done early, but the protein may not be needed once the cancer cells are formed.                   Mycoplasmas are a family of bacteria that are associated with cancers, especially in people with HIV. Researchers utilized immune-compromised mice as a model for analyzing the effect of mycoplasma infection on the development of lymphoma. They compared how quickly non-infected immune-compromised mice developed lymphoma compared to mycoplasma-infected immune-compromised mice. The mice were infected with a strai...

Stealth virus for cancer therapy

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Viral Oncology : Stealth virus for cancer therapy Scientists have redesigned an adenovirus for use in cancer therapy. They have developed a new protein shield that hides the virus and protects it from being eliminated. Adapters on the surface of the virus enable the reconstructed virus to specifically infect tumour cells.               Viruses have their own genetic material which can infect human cells in a very specific manner. They will then reproduce as directed by their own genes but using the resources of the host cell. These properties proofs that they can fight with hereditary diseases or cancer. There are uncountable different viruses, but the human adenovirus 5, which normally causes the symptoms of a typical cold, has substantial advantages. Without any of the viral genes left, the virus cannot replicate and trigger diseases . In addition, the genome of the adenovirus is very large and does not assimilate into human chromosom...