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Showing posts with the label Antimicrobial drugs

Petting zoos transmit Virulent drug-resistant bacteria to visitors

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Human infectious diseases :  Petting zoos transmit Virulent drug-resistant bacteria to visitors Petting zoos are a popular attraction around the world, allowing direct and indirect exposure of both children and adults to a diverse range of animal species. They are different from regular zoos because rather than visitors just looking at the animals, petting zoos are interactive with children visiting, holding and petting the animals. Extended spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacteriaceae (AmpC-E), which are resistant to a number of commonly used antibiotics, have become a matter of great concern in both human and veterinary medicine, so understanding the likelihood of them colonizing the animals is critical to evaluating the risk that may be posed to visitors. The researchers did a survey across randomly chosen petting zoos geographically distributed throughout the world, taking samples of faecal matter as well as from the body surface (skin, fur, or ...

Drug-Resistance in Farm Animals Threatens Human Health

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Antimicrobial Drug : Drug-Resistance in Farm Animals Threatens Human Health https://antimicrobial.vaccineconferences.com/speaker-guidelines.php In high-economic countries, where antimicrobial  have been used on farms since the 1950s, should support the transition to sustainable animal production in low & middle income countries for e.g. through a global fund to subsidize improvements in farm-level bio-safety  and bio-security , the authors advocate in the study. The Netherlands and Denmark have made a tremendous effort to reduce antimicrobial use. But these required investments in clean infrastructure and training of farmers to follow good farming practices and practicing good hygiene on the farm can reduce drug resistance in farm animals. A survey report has been done from 2000 and 2018 focusing specifically on common food-borne  pathogens, including  Escherichia coli, Campylobacter spp., non-typhoidal Salmonella,  and  Staphylococcus...

New class of Antibiotics disrupts protein synthesis

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Antimicrobial Drugs : Odilorhabdins Odilorhabdins , or ODLs, a new class of antibiotics which disrupts protein synthesis are produced by symbiotic bacteria Xenorhabdus Nematophilia , found in soil-dwelling nematode worms that colonize insects for food. The bacteria Xenorhabdus Nematophilia actually helps to kill the insect and, importantly, secrete the antibiotic to keep competating the other bacteria away. Till now, these nematode-associated bacteria and the antibiotics they make have been largely understudied. To identify the antibiotic property present in the xenorhabdus bacteria, researchers screened 80 cultured strains of the bacteria & isolated the active compounds showing properties of antibiotics, studied their chemical structures and engineered more potent derivatives. ODLs mainly act on the ribosome, which is the molecular machine of individual cells that makes the proteins it needs to function of bacterial cells. Like many clinically useful antibiotics, ODL...