2nd International conference on Antimicrobial & Antibacterial agents

A new antimicrobial-resistance gene, VCC-1, a ß-lactamase gene, has been discovered in benign close relatives of virulent Vibrio cholerae, which causes cholera. Now, researchers have found a way to block the VCC-1 enzyme, which disables that resistance gene. The research is published in the journal Antimicrobial agents & chemotherapy . VCC-1 was first found in Canada, by investigators from the Public Health Agency of Canada, on frozen shrimp that had been imported from India, and sold in a Canadian grocery store. A handful of other ß-lactamase resistance genes have also emerged from India. ß-lactamase genes code for enzymes that can break down ß-lactams, which are a critically important class of antimicrobials . The researchers identified the gene in a non-toxigenic strain of Vibrio cholerae. Since then, VCC-1 has also been found in non-toxigenic V. cholerae off of the German coastline. The danger is that it's a short jump for a gene from non-toxigenic V. cholerae to...

The timing of a hurricane is one of the common primary factors influencing its impact on the spread of mosquito-borne infectious diseases such as West Nile Virus, dengue, chikungunya and Zika etc. Researchers from Georgia State and Arizona State University developed a mathematical model to study the impact of heavy rainfall events (HREs) such as hurricanes on the transmission of vector-borne infectious diseases in temperate areas of the world, including the southern coastal U.S. In the impact of this type of extreme weather event, the mosquito population often booms in the presence of stagnant water. At the same time, the breakdown of public and private health infrastructure can set people at increased risk of infection. The study, which was published in Philosophical Transactions of the Royal Society B, found that the risk of a disease outbreak is highest if the HRE occurs early in the transmission season, or the period of time when mosquitoes are able to pass on the virus to ...

To conflict the rise of drug-resistant bacteria , researchers are developing how one superbug bacteria adapts to fight with an antibiotic of last resort, hoping to find clues that can lengthen the drug's effectiveness. Researchers at Rice University and the University Of Texas Health Science Centre at Houston ran experiments to track the biochemical changes that vancomycin-resistant Enterococci (VRE) underwent as they adapted to fight another antibiotic, daptomycin. "We need to get to a platform where we can anticipate how these pathogens will become resistant to antibiotics so we can stay one step ahead of them," said Rice biochemist Youssef Shampoo, co-author of a study in the journal Antimicrobial Agents and Chemotherapy that found VRE can develop resistance to daptomycin in more than one way. The stakes are high. In 2014, the World Health Organization reported that antibiotic-resistant infections were on pace to kill 10 million people per year worl...

              When it comes to the immune system, we usually think about lymphocytes B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses. But our immune system actually includes a lesser-known and less-studied first line of defence referred to as "innate immunity ." One of the main weapons of innate immunity is a family of small peptides, collectively known as " antimicrobial peptides" or AMPs for short. AMPs are produced by the host's (e.g. the human's) cells and combat invading microorganisms by breaking apart their cell membranes or by disrupting their functions. Despite of their importance, we know very little about AMPs. Some in vitro studies have shown that they can kill bacteria and fungi, but scientists have been hard pressed to study them in living organisms. One of the reasons is that there are simply too many factors involved in innate immunity, so isol...

                     ME Conferences invites all the participants from all over the world to attend ‘ ANTIMICROBIAL CONGRESS 2019 ’ which includes prompt Keynote Presentations, Special Sessions, Workshops, Symposiums, Oral talks, Poster Presentations, and Exhibitions. An antimicrobial is an operator who kills the microorganisms or suppresses their development. They are classified according to their mode of action on the particular microorganism. Depending upon the range of bacterial species helpless to these specialists antibacterial is classified as a wide range, intermediate-spectrum, or narrow- range. Non–pharmaceuticals antimicrobial gives a wide range of chemical and common compounds utilized as antimicrobials. The Immunology of have defence peptides gives assorted activities of HDPs. The utilize and misuse of antimicrobial drugs quickens the rise of drug-resistant strains. Post-antibiotic period alludes to a time...